effect of short-term modified alternate-day fasting on the lipid metabolism in obese women

نویسندگان

samira eshghinia

michael gadgevich gapparov

چکیده

objective: obesity is a worldwide health problem, with increasing prevalence associated with an increased risk of chronic diseases. decrease in energy intake has been shown to lower the risk of coronary artery disease (cad) in obese. the common form of dietary restriction is daily calorie restriction (cr). another form is alternate-day fasting (adf). the ability of modified adf to facilitate weight loss and lower cardiovascular risk factors has not been tested. this study examined the effects of combination cr and adf in obese adults. materials and methods: 26 female obese inpatients completed a 4 week trial of controlled food intake during modified adf period. all subjects consumed very low calorie diet on the fast day and then consumed diet including 1600 - 1700 kcal in every other day. body weight (bw) and blood pressure (bp) were measured daily. fasting blood samples were collected at the first and 29th day of trial for biochemical analysis. results: during the course of the trial (4 wk), bw of the subjects decreased (p < 0.0001) from 96.87 ± 21.34 kg to 92.16 ± 19.85 kg. mean bmi of the subjects at baseline was 37.38 ± 7.35 kg/m2, at the end of course decreased (p < 0.0001) to 35.56 ± 6.78 kg/m2. systolic bp decreased (p < 0.0001) from 142 ± 13 to 122 ± 12mm hg. total cholesterol decreased (p < 0.0001) from 6.12 ± 1.1 to 5.42 ± 1 mmol/l , ldl (p <0.0001) from 3.99 ± 0.96 to 3.34 ± 0.87 mmol/l, fasting blood sugar (p < 0.0001) from 5.87 ± 1 to 5.23 ± 0.9 mmol/l, whereas change in triacylglycerol concentrations was not significant, hdl decreased (p < 0.005) from 1.43 ± 0.38 to 1.3 ± 0.31 mmol/l . conclusion: these findings suggest that short time cr plus adf is a viable dietary option to help obese individuals lose weight and decrease systemic blood pressure and some cad risk factors. more and longer-term studies in human subjects are needed to support this important result.

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Effect of Short-Term Modified Alternate-Day Fasting on the Lipid Metabolism in Obese Women

OBJECTIVE: Obesity is a worldwide health problem, with increasing prevalence associated with an increased risk of chronic diseases. Decrease in energy intake has been shown to lower the risk of coronary artery disease (CAD) in obese. The common form of dietary restriction is daily calorie restriction (CR). Another form is alternate-day fasting (ADF). The ability of modified ADF to facilitate we...

متن کامل

Effect of Short-Term Modified Alternate-Day Fasting on the Lipid Metabolism in Obese Women

OBJECTIVE: Obesity is a worldwide health problem, with increasing prevalence associated with an increased risk of chronic diseases. Decrease in energy intake has been shown to lower the risk of coronary artery disease (CAD) in obese. The common form of dietary restriction is daily calorie restriction (CR). Another form is alternate-day fasting (ADF). The ability of modified ADF to facilitate we...

متن کامل

Effect of short-term fasting on lipid kinetics in lean and obese women.

We evaluated whole body and regional adipose tissue lipid kinetics and norepinephrine (NE) spillover during brief fasting in six lean [body mass index (BMI) 21 ± 1 kg/m2] and six upper-body obese (UBO; BMI 36 ± 1 kg/m2) women. At 14 h of fasting, abdominal adipose tissue glycerol and free fatty acid (FFA) release rates were lower ( P = 0.07), but whole body glycerol and FFA rates of appearance ...

متن کامل

The effect of regular walking and alternate day fasting on health-related factors in overweight and obese females

Introduction: Obesity is a complex health problem. The aim of this study was to determine the effects of regular walking with alternate day fasting (ADF) on health-related factors of overweight and obese females.‎  Methods: 30 healthy inactive, overweight and obese women were divided randomly into three equal groups.  The groups were: control group (BMI: 30.72±4.40 kg/m2); the experimental grou...

متن کامل

Improvements in LDL particle size and distribution by short-term alternate day modified fasting in obese adults.

Alternate day modified fasting (ADMF) beneficially modulates several indicators of CHD risk, but its effects on LDL particle size have never been tested. Accordingly, we examined the effects of ADMF on LDL particle size and distribution in obese adults. Sixteen obese subjects participated in a 10-week trial with three consecutive phases: (1) 2-week control phase; (2) 4-week ADMF controlled feed...

متن کامل

The effects of modified alternate-day fasting diet on weight loss and CAD risk factors in overweight and obese women

BACKGROUND Obesity is a worldwide health problem with increasing prevalence. Decrease in energy intake has been shown to lower the risk of coronary artery disease in obese subjects. The common form of dietary restriction is daily calorie restriction (CR). Another form is alternate-day fasting (ADF). This study examined the ability of modified ADF to facilitate weight loss and lower cardiovascul...

متن کامل

منابع من

با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید


عنوان ژورنال:
iranian journal of diabetes and obesity

جلد ۳، شماره ۱، صفحات ۱-۵

میزبانی شده توسط پلتفرم ابری doprax.com

copyright © 2015-2023